Isolation of Osteosarcoma-Associated Human Antibodies from a Combinatorial Fab Phage Display Library
نویسندگان
چکیده
منابع مشابه
Isolation of Osteosarcoma-Associated Human Antibodies from a Combinatorial Fab Phage Display Library
Osteosarcoma, a highly malignant disease, is the most common primary bone tumor and is frequently found in children and adolescents. In order to isolate antibodies against osteosarcoma antigens, a combinatorial osteosarcoma Fab library displayed on the surface of phages was used. After three rounds of selection on the surface of tumor cells, several osteosarcoma-reactive Fabs were detected. Fro...
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ژورنال
عنوان ژورنال: Journal of Biomedicine and Biotechnology
سال: 2009
ISSN: 1110-7243,1110-7251
DOI: 10.1155/2009/157531